WebJan 22, 2024 · Summary Capture Hi-C is a powerful approach for detecting chromosomal interactions involving, at least on one end, DNA regions of interest, such as gene promoters. We present Chicdiff, an R package for robust detection of … WebAug 12, 2024 · Eukaryotic genomes are highly structurally organized to allow ~10 5-fold compaction to fit within cell nuclei, while maintaining accessibility of key sequences to …
Chicdiff: a computational pipeline for detecting differential ...
WebNov 1, 2024 · Europe PMC is an archive of life sciences journal literature. Search life-sciences literature (Over 39 million articles, preprints and more) WebAug 11, 2024 · The first, Chicdiff, is our recently published method for detecting chromosomal interactions that are different between conditions in Capture Hi-C data ( Cairns et al. 2024). In our Nature Protocols article, we provide detailed instructions for running this. harry potter 3 assistir online
Chicdiff: a computational pipeline for detecting …
WebNov 9, 2024 · Hi-C is a widely used method for profiling chromosomal interactions in the 3-dimensional context. Due to limitations on the depth of sequencing, the resolution of most Hi-C datasets is often insufficient for scoring fine-scale interactions. We therefore used promoter-capture Hi-C (PCHi-C) data for mapping these subtle interactions. From … WebMay 8, 2024 · Significant chromatin interactions were identified using CHiCAGO v1.13.1 (28) using a threshold of CHiCAGO score > 5 in different conditions; cell type: CD4+T cells (n=15) and CD14+monocytes (n=15); cell type and disease state: CD4+T cells from SSc patients (n=10) and healthy controls (n=5), and CD14+ WebAug 24, 2015 · ChromDiff identifies chromatin state differences across groups of epigenomes, as described in the manuscript Systematic chromatin state comparison of … charlene hylton on facebook